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"Molecular Imaging of Vulnerable Coronary plaque whit radiolabeled Somatostatin Receptors (SSTR) J.Clin.Med."

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"Background: Venous thromboembolism (VTE) is a common disease in Latin American settings. Implementation of international guidelines in Latin American settings requires additional considerations.

Objective: To provide evidence-based guidelines about VTE prevention for Latin American patients, clinicians, and decision makers. Conclusions:

This guideline ADOLOPMENT project highlighted the importance of contextualization of recommendations in other settings, based on differences in values, resources, feasibility, and health equity impact."

Investigación y educación

"Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine. J Clin Med."

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"Abstract In the last years, new insights into the molecular basis of rheumatic conditions have been described, which have generated particular interest in understanding the pathophysiology of these diseases, in which lies the explanation of the diversity of clinical presentation and the difficulty in diagnostic and therapeutic approaches.

Investigación y educación

Imaging Activated-T-Lymphocytes in the Salivary Glands of Patients with Sjögren's Syndrome by  99m Tc-Interleukin-2: Diagnostic and Therapeutic Implications. J Clin Med.

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"Background: Sjögren’s syndrome (SS) is a progressive autoimmune disease characterized by local mononuclear cell infiltration of the salivary and lachrymal glands. Labial biopsy demonstrates local infiltration by Th1 cells that produce pro-inflammatory cytokines, such as interleukin-2 (IL2). The aim of this study was to assess the utility of 99mTc-labelled-IL2 (99mTc-IL2) in evaluating in vivo the extent and severity of lympho-mononuclear cell infiltration in the salivary glands of patients with SS.

Investigación y educación

Uptake pattern of [68Ga]Ga-DOTA-NOC in tissues: implications for inflammatory diseases. Q J Nucl Med Mol Imaging.

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"BACKGROUND: [68Ga]Ga-DOTA-NOC binds to somatostatin receptor (SSTR) subtypes 2 and 5, also expressed on lymphocytes and macrophages, but no information is available about uptake in tissues that might be affected by a chronic inflammatory process. Our aim was to obtain normal reference values for: [68Ga]Ga-DOTA-NOC uptake in tissues prone to chronic inflammation.

Investigación y educación