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Soluble concentrations of the terminal complement complex C5b-9 correlate with end-organ injury in preeclampsia.

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Valencia CM, Vargas-Rodríguez J, Bernal Y. 06/07/2022

Abstract
Objective
We sought to determine if soluble levels of C5b-9, the terminal complement complex, correlate with end-organ injury in preeclampsia.

Conclusion
We identified a pattern of increased urine and low plasma C5b-9 levels in patients with preeclampsia and end-organ injury. Soluble C5b-9 levels may be used to identify complement-mediated end-organ injury in preeclampsia.

Investigación y educación

Real-World Use of Generic Meropenem: Results of an Observational Study. Antibiotics (Basel).

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Garnica-Velandia S, Aristizábal-Ruiz LA, Alvarez-Moreno CA. 11/01/2021

Abstract
Background: To determine the therapeutic effect and tolerability of meropenem in routine clinical practice, in terms of clinical and microbiological response. Methods: A real-world, observational, descriptive, longitudinal study with daily monitoring of clinical history records was conducted on all patients who were medically prescribed meropenem during a period between October 2015 and March 2016 at a university hospital in Bucaramanga (Colombia). 

Investigación y educación

Candida auris: A Latent Threat to Critically Ill Patients with Coronavirus Disease 2019. Clin Infect Dis.

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Rodriguez JY, Le Pape P, Lopez O, Esquea K, Labiosa AL, Alvarez-Moreno C. 02/11/2021

We read the article by White et al [1] with great interest. The proposed strategy will probably elucidate the true role of coronavirus disease 2019 (COVID-19)–associated invasive fungal infections, especially COVID-19–associated pulmonary aspergillosis (CAPA). We have not found the same incidence of CAPA, probably due to the absence of an active search. However, we detected an increase in the number of fungemias in critically ill COVID-19 patients.

Investigación y educación